Hidden α-helical propensity segments within disordered regions of the transcriptional activator CHOP

C/EBP-homologous protein (CHOP) is a key determinant of the apoptotic response to endoplasmic reticulum stress or DNA damage. As a member of the C/EBP family, CHOP contains a low complexity N-terminal region involved in transcriptional activation, followed by a bZIP that binds DNA after dimerization...

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Detalles Bibliográficos
Autores principales: Canales, Ángeles, Rösinger, Marcel, Sastre, Javier, Felli, Isabella C., Jiménez-Barbero, Jesús, Giménez-Gallego, Guillermo, Fernández-Tornero, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718554/
https://www.ncbi.nlm.nih.gov/pubmed/29211802
http://dx.doi.org/10.1371/journal.pone.0189171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718554/
https://www.ncbi.nlm.nih.gov/pubmed/29211802
http://dx.doi.org/10.1371/journal.pone.0189171

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