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A promoter variant of the APOA5 gene increases atherogenic LDL levels and arterial stiffness in hypertriglyceridemic patients

Hypertriglyceridemia is recognized as an independent risk factor for coronary artery disease. The apolipoprotein A5 gene (APOA5) is a key regulator of triglyceride levels. We aimed to evaluate the associations of single nucleotide polymorphisms (SNPs) in APOA5, including -1131T>C and c.553G>T,...

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Detalles Bibliográficos
Autores principales: Kim, Minjoo, Kim, Minkyung, Yoo, Hye Jin, Lee, Eunji, Chae, Jey Sook, Lee, Sang-Hyun, Lee, Jong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718602/
https://www.ncbi.nlm.nih.gov/pubmed/29211729
http://dx.doi.org/10.1371/journal.pone.0186693