Investigating endogenous µ-opioid receptors in human keratinocytes as pharmacological targets using novel fluorescent ligand

Opioids in skin function during stress response, regeneration, ageing and, particularly in regulating sensation. In chronic pruritus, topical treatment with Naltrexone changes μ-opioid receptor (μ-OR) localization to relieve itch. The molecular mechanisms behind the effects of Naltrexone on μ-OR fun...

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Detalles Bibliográficos
Autores principales: Leong, Cheryl, Neumann, Christine, Ramasamy, Srinivas, Rout, Bhimsen, Yi Wee, Lim, Bigliardi-Qi, Mei, Bigliardi, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718609/
https://www.ncbi.nlm.nih.gov/pubmed/29211767
http://dx.doi.org/10.1371/journal.pone.0188607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718609/
https://www.ncbi.nlm.nih.gov/pubmed/29211767
http://dx.doi.org/10.1371/journal.pone.0188607

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