Chow fed UC Davis strain female Lepr fatty Zucker rats exhibit mild glucose intolerance, hypertriglyceridemia, and increased urine volume, all reduced by a Brown Norway strain chromosome 1 congenic donor region

Our objective is to identify genes that influence the development of any phenotypes of type 2 diabetes (T2D) or kidney disease in obese animals. We use the reproductively isolated UC Davis fatty Zucker strain rat model in which the defective chromosome 4 leptin receptor (Lepr(faSte/faSte)) results i...

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Detalles Bibliográficos
Autores principales: Warden, Craig H., Bettaieb, Ahmed, Min, Esther, Fisler, Janis S., Haj, Fawaz G., Stern, Judith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718614/
https://www.ncbi.nlm.nih.gov/pubmed/29211750
http://dx.doi.org/10.1371/journal.pone.0188175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718614/
https://www.ncbi.nlm.nih.gov/pubmed/29211750
http://dx.doi.org/10.1371/journal.pone.0188175

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