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Kinesin motility is driven by subdomain dynamics

The microtubule (MT)-associated motor protein kinesin utilizes its conserved ATPase head to achieve diverse motility characteristics. Despite considerable knowledge about how its ATPase activity and MT binding are coupled to the motility cycle, the atomic mechanism of the core events remain to be fo...

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Detalles Bibliográficos
Autores principales: Hwang, Wonmuk, Lang, Matthew J, Karplus, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718755/
https://www.ncbi.nlm.nih.gov/pubmed/29111975
http://dx.doi.org/10.7554/eLife.28948