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Functionally inactivated dominant viral antigens of human cytomegalovirus delivered in replication incompetent adenovirus type 6 vectors as vaccine candidates

T cell immunity is critical in controlling human cytomegalovirus (HCMV) infection in transplant recipients, and T cells targeting viral immediate early proteins such as IE1, IE2 and pp65 have been speculated to be more effective against reactivation. Here we report efforts to construct replication i...

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Detalles Bibliográficos
Autores principales: Tang, Aimin, Freed, Daniel C., Li, Fengsheng, Meschino, Steve, Prokop, Michael, Bett, Andrew, Casimiro, Danilo, Wang, Dai, Fu, Tong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718781/
https://www.ncbi.nlm.nih.gov/pubmed/28494195
http://dx.doi.org/10.1080/21645515.2017.1308988