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Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding

Ebola virus (EBOV) infection is highly lethal and results in severe febrile bleeding disorders that affect humans and non-human primates. One of the therapeutic approaches for treating EBOV infection focus largely on cocktails of monoclonal antibodies (mAbs) that bind to specific regions of the EBOV...

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Detalles Bibliográficos
Autores principales: Ripoll, Daniel R., Mitchell, Daniel A. J., Dupuy, Lesley C., Wallqvist, Anders, Schmaljohn, Connie, Chaudhury, Sidhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718834/
https://www.ncbi.nlm.nih.gov/pubmed/28922082
http://dx.doi.org/10.1080/21645515.2017.1360454