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3D microniches reveal the importance of cell size and shape

Geometrical cues have been shown to alter gene expression and differentiation on 2D substrates. However, little is known about how geometrical cues affect cell function in 3D. One major reason for this lack of understanding is rooted in the difficulties of controlling cell geometry in a complex 3D s...

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Detalles Bibliográficos
Autores principales: Bao, Min, Xie, Jing, Piruska, Aigars, Huck, Wilhelm T. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719012/
https://www.ncbi.nlm.nih.gov/pubmed/29213086
http://dx.doi.org/10.1038/s41467-017-02163-2