Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis

Leishmania parasites utilize adaptive evasion mechanisms in infected macrophages to overcome host defenses and proliferate. We report here that the PERK/eIF2α/ATF4 signaling branch of the integrated endoplasmic reticulum stress response (IERSR) is activated by Leishmania and this pathway is importan...

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Detalles Bibliográficos
Autores principales: Dias-Teixeira, Karina Luiza, Calegari-Silva, Teresa C., Medina, Jorge M., Vivarini, Áislan C., Cavalcanti, Átila, Teteo, Nataly, Santana, Alynne Karen M., Real, Fernando, Gomes, Ciro M., Pereira, Renata Meirelles Santos, Fasel, Nicolas, Silva, João S., Aktas, Bertal H., Lopes, Ulisses G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719050/
https://www.ncbi.nlm.nih.gov/pubmed/29213084
http://dx.doi.org/10.1038/s41598-017-17252-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719050/
https://www.ncbi.nlm.nih.gov/pubmed/29213084
http://dx.doi.org/10.1038/s41598-017-17252-x

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