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The conserved ancient role of chordate PIAS as a multilevel repressor of the NF-κB pathway
In vertebrates, PIAS genes encode versatile cellular regulators, with functions extremely complex and redundant. Here we try to understand their functions from an evolutionary perspective. we evaluate the sequences, expression and molecular functions of amphioxus PIAS genes and compare them with the...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719053/ https://www.ncbi.nlm.nih.gov/pubmed/29213053 http://dx.doi.org/10.1038/s41598-017-16624-7 |