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Nitric oxide mediates apoptosis and mitochondrial dysfunction and plays a role in growth hormone deficiency by nivalenol in GH3 cells

Nivalenol (NIV), a type B trichothecenes commonly found in cereal crops, can cause growth impairment in animals. However, limited information about its mechanisms is available. Trichothecenes have been characterized as an inhibitor of protein synthesis and induce apoptosis in cells. Oxidative stress...

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Detalles Bibliográficos
Autores principales: Huang, Deyu, Cui, Luqing, Guo, Pu, Xue, Xijuan, Wu, Qinghua, Hussain, Hafiz Iftikhar, Wang, Xu, Yuan, Zonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719085/
https://www.ncbi.nlm.nih.gov/pubmed/29213091
http://dx.doi.org/10.1038/s41598-017-16908-y