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Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide

Non-viral gene delivery systems have gained considerable attention as a promising alternative to viral delivery to treat diseases associated with aberrant gene expression. However, regardless of extensive research, only a little is known about the parameters that underline in vivo use of the nanopar...

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Detalles Bibliográficos
Autores principales: Kurrikoff, Kaido, Veiman, Kadi-Liis, Künnapuu, Kadri, Peets, Elin Madli, Lehto, Tõnis, Pärnaste, Ly, Arukuusk, Piret, Langel, Ülo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719086/
https://www.ncbi.nlm.nih.gov/pubmed/29213085
http://dx.doi.org/10.1038/s41598-017-17316-y