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Treatment of melanoma with selected inhibitors of signaling kinases effectively reduces proliferation and induces expression of cell cycle inhibitors

Cancer treatment often tends to involve direct targeting enzymes essential for the growth and proliferation of cancer cells. The aim of this study was the recognition of the possible role of selected protein kinases: PI3K, ERK1/2, and mTOR in cell proliferation and cell cycle in malignant melanoma....

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Detalles Bibliográficos
Autores principales: Ciołczyk-Wierzbicka, Dorota, Gil, Dorota, Laidler, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719123/
https://www.ncbi.nlm.nih.gov/pubmed/29214525
http://dx.doi.org/10.1007/s12032-017-1069-0