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Pumilio2-deficient mice show a predisposition for epilepsy

Epilepsy is a neurological disease that is caused by abnormal hypersynchronous activities of neuronal ensembles leading to recurrent and spontaneous seizures in human patients. Enhanced neuronal excitability and a high level of synchrony between neurons seem to trigger these spontaneous seizures. Th...

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Detalles Bibliográficos
Autores principales: Follwaczny, Philipp, Schieweck, Rico, Riedemann, Therese, Demleitner, Antonia, Straub, Tobias, Klemm, Anna H., Bilban, Martin, Sutor, Bernd, Popper, Bastian, Kiebler, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719250/
https://www.ncbi.nlm.nih.gov/pubmed/29046322
http://dx.doi.org/10.1242/dmm.029678