Cargando…
RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus
During the development of autoimmune disease, a switch occurs in the antibody repertoire of B cells so that the production of pathogenic rather than non-pathogenic autoantibodies is enabled. However, there is limited knowledge concerning how this pivotal step occurs. Here, we present genetic and pha...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719251/ https://www.ncbi.nlm.nih.gov/pubmed/28882929 http://dx.doi.org/10.1242/dmm.029835 |