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Structural analysis of the complex between influenza B nucleoprotein and human importin-α

Influenza viruses are negative strand RNA viruses that replicate in the nucleus of the cell. The viral nucleoprotein (NP) is the major component of the viral ribonucleoprotein. In this paper we show that the NP of influenza B has a long N-terminal tail of 70 residues with intrinsic flexibility. This...

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Detalles Bibliográficos
Autores principales: Labaronne, Alice, Milles, Sigrid, Donchet, Amélie, Jensen, Malene Ringkjøbing, Blackledge, Martin, Bourhis, Jean-Marie, Ruigrok, Rob W. H., Crépin, Thibaut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719345/
https://www.ncbi.nlm.nih.gov/pubmed/29215074
http://dx.doi.org/10.1038/s41598-017-17458-z