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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods

The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analysis very...

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Detalles Bibliográficos
Autores principales: Vander Plaetsen, Ann-Sophie, Deleye, Lieselot, Cornelis, Senne, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Deforce, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719346/
https://www.ncbi.nlm.nih.gov/pubmed/29215049
http://dx.doi.org/10.1038/s41598-017-17525-5