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STR profiling and Copy Number Variation analysis on single, preserved cells using current Whole Genome Amplification methods
The growing interest in liquid biopsies for cancer research and cell-based non-invasive prenatal testing (NIPT) invigorates the need for improved single cell analysis. In these applications, target cells are extremely rare and fragile in peripheral circulation, which makes the genetic analysis very...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719346/ https://www.ncbi.nlm.nih.gov/pubmed/29215049 http://dx.doi.org/10.1038/s41598-017-17525-5 |