CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system revolutionized the field of gene editing but viral delivery of the CRISPR/Cas9 system has not been fully explored. Here we adapted clinically relevant high-capacity adenoviral vectors (HCAdV) devoid of all viral genes...

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Detalles Bibliográficos
Autores principales: Ehrke-Schulz, Eric, Schiwon, Maren, Leitner, Theo, Dávid, Stephan, Bergmann, Thorsten, Liu, Jing, Ehrhardt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719366/
https://www.ncbi.nlm.nih.gov/pubmed/29215041
http://dx.doi.org/10.1038/s41598-017-17180-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719366/
https://www.ncbi.nlm.nih.gov/pubmed/29215041
http://dx.doi.org/10.1038/s41598-017-17180-w

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