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CRISPR/Cas9 delivery with one single adenoviral vector devoid of all viral genes
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system revolutionized the field of gene editing but viral delivery of the CRISPR/Cas9 system has not been fully explored. Here we adapted clinically relevant high-capacity adenoviral vectors (HCAdV) devoid of all viral genes...
Autores principales: | Ehrke-Schulz, Eric, Schiwon, Maren, Leitner, Theo, Dávid, Stephan, Bergmann, Thorsten, Liu, Jing, Ehrhardt, Anja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719366/ https://www.ncbi.nlm.nih.gov/pubmed/29215041 http://dx.doi.org/10.1038/s41598-017-17180-w |
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