TRAF3 negatively regulates platelet activation and thrombosis

CD40 ligand (CD40L), a member of the tumor necrosis factor (TNF) superfamily, binds to CD40, leading to many effects depending on target cell type. Platelets express CD40L and are a major source of soluble CD40L. CD40L has been shown to potentiate platelet activation and thrombus formation, involvin...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Zhang, Guoying, Xiang, Binggang, Chen, Xiaofeng, Tang, Lijang, Shi, Shaojun, Liu, Yani, Ai, Xun, Xie, Ping, Li, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719392/
https://www.ncbi.nlm.nih.gov/pubmed/29215030
http://dx.doi.org/10.1038/s41598-017-17189-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719392/
https://www.ncbi.nlm.nih.gov/pubmed/29215030
http://dx.doi.org/10.1038/s41598-017-17189-1

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