Cargando…

TRAF3 negatively regulates platelet activation and thrombosis

CD40 ligand (CD40L), a member of the tumor necrosis factor (TNF) superfamily, binds to CD40, leading to many effects depending on target cell type. Platelets express CD40L and are a major source of soluble CD40L. CD40L has been shown to potentiate platelet activation and thrombus formation, involvin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Rui, Zhang, Guoying, Xiang, Binggang, Chen, Xiaofeng, Tang, Lijang, Shi, Shaojun, Liu, Yani, Ai, Xun, Xie, Ping, Li, Zhenyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719392/ https://www.ncbi.nlm.nih.gov/pubmed/29215030 http://dx.doi.org/10.1038/s41598-017-17189-1

Ejemplares similares

The P2Y(12) Antagonists, 2MeSAMP and Cangrelor, Inhibit Platelet Activation through P2Y(12)/G(i)-Dependent Mechanism
por: Xiang, Binggang, et al.
Publicado: (2012)

MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis
por: Ding, Yangyang, et al.
Publicado: (2023)

Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production
por: Zhang, Sixuan, et al.
Publicado: (2021)

NOTCH2 negatively regulates metastasis and epithelial-Mesenchymal transition via TRAF6/AKT in nasopharyngeal carcinoma
por: Zou, You, et al.
Publicado: (2019)

The relationship between TRAF6 and tumors
por: Li, Jiaoduan, et al.
Publicado: (2020)

TRAF molecules in cell signaling and in human diseases
por: Xie, Ping
Publicado: (2013)

Chicken miR-126-5p negatively regulates antiviral innate immunity by targeting TRAF3
por: Wang, Jie, et al.
Publicado: (2022)

Regulator of G‐Protein Signaling 16 Is a Negative Modulator of Platelet Function and Thrombosis
por: Hernandez, Keziah R., et al.
Publicado: (2019)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro
por: Tian, Feng, et al.
Publicado: (2020)

Cell type-specific function of TRAF2 and TRAF3 in regulating type I IFN induction
por: Xie, Xiaoping, et al.
Publicado: (2019)

Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis
por: Flora, Gagan D., et al.
Publicado: (2019)

BICP0 Negatively Regulates TRAF6-Mediated NF-κB and Interferon Activation by Promoting K48-Linked Polyubiquitination of TRAF6
por: Cao, Chong, et al.
Publicado: (2020)

HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1
por: Peng, Yanyan, et al.
Publicado: (2014)

Comparison of Target Recognition by TRAF1 and TRAF2
por: Kim, Chang Min, et al.
Publicado: (2020)

HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex
por: Mao, He-Ting, et al.
Publicado: (2016)

Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6
por: Min, Yoon, et al.
Publicado: (2016)

TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin
por: Luo, Zhongling, et al.
Publicado: (2016)

Predictive value of platelet aggregation rate in postpartum deep venous thrombosis and its possible mechanism
por: Sun, Mingxia, et al.
Publicado: (2018)

Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1
por: Huang, Jing-Ping, et al.
Publicado: (2023)

Genetic Alterations of TRAF Proteins in Human Cancers
por: Zhu, Sining, et al.
Publicado: (2018)

Coagulopathy is associated with multiple organ damage and prognosis of COVID-19
por: Zhang, Rui, et al.
Publicado: (2021)

Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling
por: Arron, Joseph R., et al.
Publicado: (2002)

Roxadustat Does Not Affect Platelet Production, Activation, and Thrombosis Formation
por: Zhao, Jiaxin, et al.
Publicado: (2021)

Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway
por: Kim, Chang Min, et al.
Publicado: (2016)

TRAF3: A novel regulator of mitochondrial physiology and metabolic pathways in B lymphocytes
por: Jung, Jaeyong, et al.
Publicado: (2023)

Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome
por: Zhang, Liting, et al.
Publicado: (2018)

Cancer and Thrombosis: The Platelet Perspective
por: Meikle, Claire K. S., et al.
Publicado: (2017)

Platelet Aggregation Tests and Thrombosis
por: O'Brien, J. R.
Publicado: (1969)

Platelets as Mediators of Neuroinflammation and Thrombosis
por: Rawish, Elias, et al.
Publicado: (2020)

Platelet–Neutrophil Crosstalk in Thrombosis
por: Mereweather, Laura J., et al.
Publicado: (2023)

Prognostic Significance of TNFR-Associated Factor 1 and 2 (TRAF1 and TRAF2) in Glioblastoma
por: Zhang, Wenqing, et al.
Publicado: (2017)

423 An omega-6-derived eicosanoid negatively regulates platelet reactivity of cardiovascular patients at increased risk for thrombosis
por: Yamaguchi, Adriana, et al.
Publicado: (2023)

Different Activation of TRAF4 and TRAF6 in Inflammatory Bowel Disease
por: Shen, Jun, et al.
Publicado: (2013)

IFT80 negatively regulates osteoclast differentiation via association with Cbl-b to disrupt TRAF6 stabilization and activation
por: Deepak, Vishwa, et al.
Publicado: (2022)

SHARPIN Negatively Associates with TRAF2-Mediated NFκB Activation
por: Liang, Yanhua
Publicado: (2011)

Dominant Negative TRAF3 Variant With Recurrent Mycobacterium abscessus Infection and Bronchiectasis
por: Liew, Mei Fong, et al.
Publicado: (2022)

The Roles of TRAF3 in Immune Responses
por: Lin, Mengjiao, et al.
Publicado: (2023)

Novel Findings in Teleost TRAF4, a Protein Acts as an Enhancer in TRIF and TRAF6 Mediated Antiviral and Inflammatory Signaling
por: Chen, Ying, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_blkthp8i84p34eahkco1o86k1q