Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease

Influenza is a serious hazard to human health that causes hundreds of thousands of deaths annually. Though vaccines and current therapeutics can blunt some of the perilous impact of this viral infection, new treatments are needed due to the constantly evolving nature of this virus. Recently, our gro...

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Detalles Bibliográficos
Autores principales: Beylkin, Diane, Kumar, Gyanendra, Zhou, Wei, Park, Jaehyeon, Jeevan, Trushar, Lagisetti, Chandraiah, Harfoot, Rhodri, Webby, Richard J., White, Stephen W., Webb, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719402/
https://www.ncbi.nlm.nih.gov/pubmed/29215062
http://dx.doi.org/10.1038/s41598-017-17419-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719402/
https://www.ncbi.nlm.nih.gov/pubmed/29215062
http://dx.doi.org/10.1038/s41598-017-17419-6

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