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Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus
Wnt proteins direct embryonic patterning, but the regulatory basis of their distribution and signal reception remain unclear. Here, we show that endogenous Wnt8 protein is distributed in a graded manner in Xenopus embryo and accumulated on the cell surface in a punctate manner in association with “N...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719454/ https://www.ncbi.nlm.nih.gov/pubmed/29215008 http://dx.doi.org/10.1038/s41467-017-02076-0 |