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Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus

Wnt proteins direct embryonic patterning, but the regulatory basis of their distribution and signal reception remain unclear. Here, we show that endogenous Wnt8 protein is distributed in a graded manner in Xenopus embryo and accumulated on the cell surface in a punctate manner in association with “N...

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Detalles Bibliográficos
Autores principales: Mii, Yusuke, Yamamoto, Takayoshi, Takada, Ritsuko, Mizumoto, Shuji, Matsuyama, Makoto, Yamada, Shuhei, Takada, Shinji, Taira, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719454/
https://www.ncbi.nlm.nih.gov/pubmed/29215008
http://dx.doi.org/10.1038/s41467-017-02076-0