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Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning

BACKGROUND: TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcriptional chromatin alterations include subtle changes in nu...

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Detalles Bibliográficos
Autores principales: Gutiérrez, Gabriel, Millán-Zambrano, Gonzalo, Medina, Daniel A., Jordán-Pla, Antonio, Pérez-Ortín, José E., Peñate, Xenia, Chávez, Sebastián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719526/
https://www.ncbi.nlm.nih.gov/pubmed/29212533
http://dx.doi.org/10.1186/s13072-017-0165-x