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Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning
BACKGROUND: TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcriptional chromatin alterations include subtle changes in nu...
Autores principales: | Gutiérrez, Gabriel, Millán-Zambrano, Gonzalo, Medina, Daniel A., Jordán-Pla, Antonio, Pérez-Ortín, José E., Peñate, Xenia, Chávez, Sebastián |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719526/ https://www.ncbi.nlm.nih.gov/pubmed/29212533 http://dx.doi.org/10.1186/s13072-017-0165-x |
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