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Protein kinase C α enhances migration of breast cancer cells through FOXC2-mediated repression of p120-catenin

BACKGROUND: Despite recent advances in the diagnosis and treatment of breast cancer, metastasis remains the main cause of death. Since migration of tumor cells is considered a prerequisite for tumor cell invasion and metastasis, a pressing goal in tumor biology has been to elucidate factors regulati...

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Detalles Bibliográficos
Autores principales: Pham, Thao N. D., Perez White, Bethany E., Zhao, Huiping, Mortazavi, Fariborz, Tonetti, Debra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719564/
https://www.ncbi.nlm.nih.gov/pubmed/29216867
http://dx.doi.org/10.1186/s12885-017-3827-y