On the impact of relatedness on SNP association analysis

BACKGROUND: When testing for SNP (single nucleotide polymorphism) associations in related individuals, observations are not independent. Simple linear regression assuming independent normally distributed residuals results in an increased type I error and the power of the test is also affected in a m...

Descripción completa

Detalles Bibliográficos
Autores principales: Gross, Arnd, Tönjes, Anke, Scholz, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719591/
https://www.ncbi.nlm.nih.gov/pubmed/29212447
http://dx.doi.org/10.1186/s12863-017-0571-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719591/
https://www.ncbi.nlm.nih.gov/pubmed/29212447
http://dx.doi.org/10.1186/s12863-017-0571-x

Ejemplares similares