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Emodin Impairs Radioresistance of Human Osteosarcoma Cells by Suppressing Sonic Hedgehog Signaling

BACKGROUND: This study aimed to investigate the possible involvement of sonic hedgehog (Shh) signaling in the radioresistance of human osteosarcoma cells and the inhibitory effects of emodin on radioresistance. MATERIAL/METHODS: Human osteosarcoma (OS) cell line MG63 was employed as parent cells. Af...

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Detalles Bibliográficos
Autores principales: Qu, Wei, Wang, Yufei, Wu, Qining, Hao, Dingjun, Li, Dichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719725/
https://www.ncbi.nlm.nih.gov/pubmed/29203762
http://dx.doi.org/10.12659/MSM.907453