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Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome

BACKGROUND: The NLRP3 inflammasome activation and neuroinflammation are known to be involved in the pathology of depression, whereas autophagy has multiple effects on immunity, which is partly mediated by the regulation of inflammasome and clearance of proinflammatory cytokines. Given the emerging e...

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Detalles Bibliográficos
Autores principales: Jiang, Pei, Guo, Yujin, Dang, Ruili, Yang, Mengqi, Liao, Dehua, Li, Huande, Sun, Zhen, Feng, Qingyan, Xu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719935/
https://www.ncbi.nlm.nih.gov/pubmed/29212498
http://dx.doi.org/10.1186/s12974-017-1013-4