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Rules for functional microRNA targeting

MicroRNAs (miRNAs) are ~22nt-long single-stranded RNA molecules that form a RNA-induced silencing complex with Argonaute (AGO) protein to post-transcriptionally downregulate their target messenger RNAs (mRNAs). To understand the regulatory mechanisms of miRNA, discovering the underlying functional r...

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Detalles Bibliográficos
Autores principales: Kim, Doyeon, Chang, Hee Ryung, Baek, Daehyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720468/
https://www.ncbi.nlm.nih.gov/pubmed/28946941
http://dx.doi.org/10.5483/BMBRep.2017.50.11.179