PD-1 deficiency protects experimental colitis via alteration of gut microbiota

Programmed cell death-1 (PD-1) is a coinhibitory molecule and plays a pivotal role in immune regulation. Here, we demonstrate a role for PD-1 in pathogenesis of inflammatory bowel disease (IBD). Wild-type (WT) mice had severe wasting disease during experimentally induced colitis, while mice deficien...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Seong Jeong, Kim, Ji-Hae, Song, Mi-Young, Sung, Young Chul, Lee, Seung-Woo, Park, Yunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720472/
https://www.ncbi.nlm.nih.gov/pubmed/29065967
http://dx.doi.org/10.5483/BMBRep.2017.50.11.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720472/
https://www.ncbi.nlm.nih.gov/pubmed/29065967
http://dx.doi.org/10.5483/BMBRep.2017.50.11.165

Ejemplares similares