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Nodal patterning without Lefty inhibitory feedback is functional but fragile
Developmental signaling pathways often activate their own inhibitors. Such inhibitory feedback has been suggested to restrict the spatial and temporal extent of signaling or mitigate signaling fluctuations, but these models are difficult to rigorously test. Here, we determine whether the ability of...
Autores principales: | Rogers, Katherine W, Lord, Nathan D, Gagnon, James A, Pauli, Andrea, Zimmerman, Steven, Aksel, Deniz C, Reyon, Deepak, Tsai, Shengdar Q, Joung, J Keith, Schier, Alexander F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720593/ https://www.ncbi.nlm.nih.gov/pubmed/29215332 http://dx.doi.org/10.7554/eLife.28785 |
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