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Immune-mediated inflammatory diseases differently affect IGRAs’ accuracy for latent tuberculosis infection diagnosis in clinical practice

BACKGROUND: Clinical accuracy of IGRAs remains unclear on patients with immune-mediated inflammatory diseases (IMIDs). Here, we assess the impact of immunosuppressants and IMIDs on QuantiFERON-TB Gold In-Tube (QFN-G-IT) and T-SPOT.TB accuracy. METHODS: Patients with IMIDs who required latent tubercu...

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Detalles Bibliográficos
Autores principales: Latorre, Irene, Mínguez, Sonia, Carrascosa, José-Manuel, Naves, Juan, Villar-Hernández, Raquel, Muriel, Beatriz, Prat, Cristina, García-García, Esther, Casas, Irma, Domènech, Eugeni, Ferrándiz, Carlos, Mateo, Lourdes, Domínguez, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720599/
https://www.ncbi.nlm.nih.gov/pubmed/29216277
http://dx.doi.org/10.1371/journal.pone.0189202