Functional analysis of a CDKN2A 5’UTR germline variant associated with pancreatic cancer development

CDKN2A coding region germline variants are associated with pancreatic adenocarcinoma (PC) susceptibility. Recently, we described functional germline 5’UTR CDKN2A variants from melanoma patients affecting the post-transcriptional regulation of p16(INK4a) mRNA that is dependent, at least in part, on a...

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Detalles Bibliográficos
Autores principales: Bruno, William, Andreotti, Virginia, Bisio, Alessandra, Pastorino, Lorenza, Fornarini, Giuseppe, Sciallero, Stefania, Bianchi-Scarrà, Giovanna, Inga, Alberto, Ghiorzo, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720692/
https://www.ncbi.nlm.nih.gov/pubmed/29216274
http://dx.doi.org/10.1371/journal.pone.0189123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720692/
https://www.ncbi.nlm.nih.gov/pubmed/29216274
http://dx.doi.org/10.1371/journal.pone.0189123

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