Global computational mutagenesis provides a critical stability framework in protein structures

A protein’s amino acid sequence dictates the folds and final structure the macromolecule will form. We propose that by identifying critical residues in a protein’s atomic structure, we can select a critical stability framework within the protein structure essential to proper protein folding. We use...

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Detalles Bibliográficos
Autores principales: McCafferty, Caitlyn L., Sergeev, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720693/
https://www.ncbi.nlm.nih.gov/pubmed/29216252
http://dx.doi.org/10.1371/journal.pone.0189064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720693/
https://www.ncbi.nlm.nih.gov/pubmed/29216252
http://dx.doi.org/10.1371/journal.pone.0189064

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