Protamine neutralizes chondroitin sulfate proteoglycan-mediated inhibition of oligodendrocyte differentiation

Chondroitin sulfate proteoglycans (CSPGs), which are enriched in demyelinating plaques in neurodegenerative diseases, such as multiple sclerosis (MS), impair remyelination by inhibiting the migration and differentiation of oligodendrocyte precursor cells (OPCs) in the central nervous system (CNS). W...

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Detalles Bibliográficos
Autores principales: Kuboyama, Kazuya, Tanga, Naomi, Suzuki, Ryoko, Fujikawa, Akihiro, Noda, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720700/
https://www.ncbi.nlm.nih.gov/pubmed/29216327
http://dx.doi.org/10.1371/journal.pone.0189164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720700/
https://www.ncbi.nlm.nih.gov/pubmed/29216327
http://dx.doi.org/10.1371/journal.pone.0189164

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