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Systematic integrative analysis of gene expression identifies HNF4A as the central gene in pathogenesis of non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world, and encompasses a spectrum from simple steatosis to steatohepatitis (NASH). There is currently no approved pharmacologic therapy against NASH, partly due to an incomplete understanding of its mol...

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Detalles Bibliográficos
Autores principales: Baciu, Cristina, Pasini, Elisa, Angeli, Marc, Schwenger, Katherine, Afrin, Jenifar, Humar, Atul, Fischer, Sandra, Patel, Keyur, Allard, Johane, Bhat, Mamatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720788/
https://www.ncbi.nlm.nih.gov/pubmed/29216278
http://dx.doi.org/10.1371/journal.pone.0189223