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Safety and efficacy of a freeze-dried trivalent antivenom for snakebites in the Brazilian Amazon: An open randomized controlled phase IIb clinical trial

BACKGROUND: In tropical areas, a major concern regarding snakebites treatment effectiveness relates to the failure in liquid antivenom (AV) distribution due to the lack of an adequate cold chain in remote areas. To minimize this problem, freeze-drying has been suggested to improve AV stability. METH...

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Detalles Bibliográficos
Autores principales: Mendonça-da-Silva, Iran, Magela Tavares, Antônio, Sachett, Jacqueline, Sardinha, José Felipe, Zaparolli, Lilian, Gomes Santos, Maria Fátima, Lacerda, Marcus, Monteiro, Wuelton Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720814/
https://www.ncbi.nlm.nih.gov/pubmed/29176824
http://dx.doi.org/10.1371/journal.pntd.0006068