Vaccine-elicited memory CD4(+) T cell expansion is impaired in the lungs during tuberculosis

Immunological memory is the key biological process that makes vaccines possible. Although tuberculosis vaccines elicit protective immunity in animals, few provide durable protection. To understand why protection is transient, we evaluated the ability of memory CD4(+) T cells to expand, differentiate...

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Detalles Bibliográficos
Autores principales: Carpenter, Stephen M., Yang, Jason D., Lee, Jinhee, Barreira-Silva, Palmira, Behar, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720822/
https://www.ncbi.nlm.nih.gov/pubmed/29176787
http://dx.doi.org/10.1371/journal.ppat.1006704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720822/
https://www.ncbi.nlm.nih.gov/pubmed/29176787
http://dx.doi.org/10.1371/journal.ppat.1006704

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