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Vaccine-elicited memory CD4(+) T cell expansion is impaired in the lungs during tuberculosis
Immunological memory is the key biological process that makes vaccines possible. Although tuberculosis vaccines elicit protective immunity in animals, few provide durable protection. To understand why protection is transient, we evaluated the ability of memory CD4(+) T cells to expand, differentiate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5720822/ https://www.ncbi.nlm.nih.gov/pubmed/29176787 http://dx.doi.org/10.1371/journal.ppat.1006704 |