Cargando…
Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents
Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on thes...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721122/ https://www.ncbi.nlm.nih.gov/pubmed/29039082 http://dx.doi.org/10.1007/s10555-017-9701-1 |