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Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents

Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on thes...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Yang, Qianqian, Xiao, Lu, Tang, Daolin, Dou, Q. Ping, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721122/
https://www.ncbi.nlm.nih.gov/pubmed/29039082
http://dx.doi.org/10.1007/s10555-017-9701-1