Cargando…
Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents
Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on thes...
Autores principales: | Chen, Xin, Yang, Qianqian, Xiao, Lu, Tang, Daolin, Dou, Q. Ping, Liu, Jinbao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721122/ https://www.ncbi.nlm.nih.gov/pubmed/29039082 http://dx.doi.org/10.1007/s10555-017-9701-1 |
Ejemplares similares
-
Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
por: Liu, Ningning, et al.
Publicado: (2015) -
Clinically used antirheumatic agent auranofin is a proteasomal
deubiquitinase inhibitor and inhibits tumor growth
por: Liu, Ningning, et al.
Publicado: (2014) -
Targeting Ubiquitin–Proteasome System With Copper Complexes for Cancer Therapy
por: Chen, Xin, et al.
Publicado: (2021) -
A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases
por: Liu, Ningning, et al.
Publicado: (2014) -
Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma
por: Jiang, Liling, et al.
Publicado: (2019)