Cargando…

Making sense of snapshot data: ergodic principle for clonal cell populations

Population growth is often ignored when quantifying gene expression levels across clonal cell populations. We develop a framework for obtaining the molecule number distributions in an exponentially growing cell population taking into account its age structure. In the presence of generation time vari...

Descripción completa

Detalles Bibliográficos
Autor principal: Thomas, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721154/
https://www.ncbi.nlm.nih.gov/pubmed/29187636
http://dx.doi.org/10.1098/rsif.2017.0467