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Making sense of snapshot data: ergodic principle for clonal cell populations
Population growth is often ignored when quantifying gene expression levels across clonal cell populations. We develop a framework for obtaining the molecule number distributions in an exponentially growing cell population taking into account its age structure. In the presence of generation time vari...
Autor principal: | Thomas, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721154/ https://www.ncbi.nlm.nih.gov/pubmed/29187636 http://dx.doi.org/10.1098/rsif.2017.0467 |
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