Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling

Epithelial–mesenchymal transition (EMT) plays key roles during embryonic development, wound healing and cancer metastasis. Cells in a partial EMT or hybrid epithelial/mesenchymal (E/M) phenotype exhibit collective cell migration, forming clusters of circulating tumour cells—the primary drivers of me...

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Detalles Bibliográficos
Autores principales: Bocci, Federico, Jolly, Mohit K., Tripathi, Satyendra C., Aguilar, Mitzi, Hanash, Samir M., Levine, Herbert, Onuchic, José N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Life Sciences–Physics interface
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721160/
https://www.ncbi.nlm.nih.gov/pubmed/29187638
http://dx.doi.org/10.1098/rsif.2017.0512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721160/
https://www.ncbi.nlm.nih.gov/pubmed/29187638
http://dx.doi.org/10.1098/rsif.2017.0512

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