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MicroRNA Expression-Based Model Indicates Event-Free Survival in Pediatric Acute Myeloid Leukemia

PURPOSE: Children with acute myeloid leukemia (AML) whose disease is refractory to standard induction chemotherapy therapy or who experience relapse after initial response have dismal outcomes. We sought to comprehensively profile pediatric AML microRNA (miRNA) samples to identify dysregulated genes...

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Detalles Bibliográficos
Autores principales: Lim, Emilia L., Trinh, Diane L., Ries, Rhonda E., Wang, Jim, Gerbing, Robert B., Ma, Yussanne, Topham, James, Hughes, Maya, Pleasance, Erin, Mungall, Andrew J., Moore, Richard, Zhao, Yongjun, Aplenc, Richard, Sung, Lillian, Kolb, E. Anders, Gamis, Alan, Smith, Malcolm, Gerhard, Daniela S., Alonzo, Todd A., Meshinchi, Soheil, Marra, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721230/
https://www.ncbi.nlm.nih.gov/pubmed/29068783
http://dx.doi.org/10.1200/JCO.2017.74.7451