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Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin

Langerhans’ cells (LC) play pivotal roles in skin immune responses, linking innate and adaptive immunity. In aged skin there are fewer LC and migration is impaired compared with young skin. These changes may contribute to declining skin immunity in the elderly, including increased skin infections an...

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Detalles Bibliográficos
Autores principales: Pilkington, Suzanne M., Ogden, Stephanie, Eaton, Laura H., Dearman, Rebecca J., Kimber, Ian, Griffiths, Christopher E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243/
https://www.ncbi.nlm.nih.gov/pubmed/28777886
http://dx.doi.org/10.1111/imm.12810