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Lower levels of interleukin‐1β gene expression are associated with impaired Langerhans’ cell migration in aged human skin
Langerhans’ cells (LC) play pivotal roles in skin immune responses, linking innate and adaptive immunity. In aged skin there are fewer LC and migration is impaired compared with young skin. These changes may contribute to declining skin immunity in the elderly, including increased skin infections an...
Autores principales: | Pilkington, Suzanne M., Ogden, Stephanie, Eaton, Laura H., Dearman, Rebecca J., Kimber, Ian, Griffiths, Christopher E. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721243/ https://www.ncbi.nlm.nih.gov/pubmed/28777886 http://dx.doi.org/10.1111/imm.12810 |
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