Increased ethanol‐inducible cytochrome P450‐2E1 and cytochrome P450 isoforms in exosomes of alcohol‐exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress

This study investigated the role of ethanol‐inducible cytochrome P450‐2E1 (CYP2E1) in enhancing CYP2E1 and other P450 proteins in extracellular vesicles (EVs) from alcohol‐exposed rodents and human patients with alcoholism and their effects on oxidative hepatocyte injury. Female Fischer rats and wil...

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Detalles Bibliográficos
Autores principales: Cho, Young‐Eun, Mezey, Esteban, Hardwick, James P., Salem, Norman, Clemens, Dahn L., Song, Byoung‐Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721437/
https://www.ncbi.nlm.nih.gov/pubmed/29404485
http://dx.doi.org/10.1002/hep4.1066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721437/
https://www.ncbi.nlm.nih.gov/pubmed/29404485
http://dx.doi.org/10.1002/hep4.1066

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